Sofia Khan
Papers
1
Total Citations
6
H-Index
1
About
Sofia Khan is a cancer biology researcher whose work centers on preclinical modeling of prostate cancer, with a particular focus on advancing the fidelity of experimental systems used to study this disease. Her most notable contribution, "Critical Evaluation of the Subcutaneous Engraftments of Hormone Naïve Primary Prostate Cancer" (2020), addresses a significant gap in the field: the scarcity of reliable patient-derived xenograft (PDX) models derived from hormone naïve primary prostate cancer. PDX models are widely valued for their ability to preserve the histopathological and molecular heterogeneity of human tumors, making them superior to many conventional preclinical systems. Through rigorous critical evaluation, Khan's work sheds light on the challenges and limitations of subcutaneous engraftment approaches, providing the research community with crucial insights for improving model development. Though her paper has accumulated 6 citations since publication, its contribution lies in tackling a persistent bottleneck in translational prostate cancer research — one with direct implications for drug development and personalized medicine. Khan's research represents an important step toward more accurate and clinically relevant preclinical platforms for studying one of the most prevalent cancers affecting men worldwide.
Research Focus
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Top Papers
- 1