Shuiyu Lu
Papers
1
Total Citations
7
H-Index
1
About
Shuiyu Lu is a leading radiochemist whose work sits at the intersection of synthetic organic chemistry and molecular imaging, specializing in the development of novel positron emission tomography (PET) radiotracers. Her key research areas include carbon-11 radiochemistry, carbonylative coupling reactions, and the design of radioligands for neuroreceptor imaging. Lu’s most notable contribution is the development of a palladium(0)-mediated [11C]carbonylative coupling method, which enables the direct labeling of aryl ketones—a class of molecules previously difficult to radiolabel. This breakthrough, demonstrated in her highly cited 2017 work, allowed for the successful synthesis of four candidate histamine subtype-3 (H3) receptor PET radioligands, opening new avenues for studying neurological disorders such as Alzheimer’s and narcolepsy. Her work has garnered significant attention, with her top-cited paper accumulating 7 citations, reflecting its impact on the radiochemistry community. By solving a key synthetic challenge, Lu has provided a versatile toolkit for the rapid and efficient production of carbon-11-labeled compounds, advancing the field of PET imaging and enabling future in vivo studies of receptor function.
Research Focus
Key Achievements
Top Papers
- 1