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About

Shelagh Lovell is a pioneering translational researcher whose work bridges molecular imaging and surgical oncology, with a primary focus on improving outcomes for prostate cancer patients. Her key research areas include intraoperative fluorescence guidance, molecularly targeted imaging agents, and the clinical translation of novel theranostic tools. Lovell’s major contribution is her leadership in the first-in-human study of the PSMA Minibody IR800-IAB2M, a humanised antibody fragment conjugated to a near-infrared fluorophore, designed to enable real-time visualisation of prostate cancer during robot-assisted radical prostatectomy. This landmark work, published in 2024 and already garnering 18 citations, demonstrates her ability to move cutting-edge molecular probes from bench to bedside, offering the potential to reduce positive surgical margins and improve surgical precision. Her research has significant clinical impact, as it directly addresses the challenge of intraoperative tumour detection, and her achievements include pioneering the use of PSMA-targeted fluorescence guidance in a surgical setting. Lovell’s work is essential reading for researchers and clinicians interested in image-guided surgery, molecular imaging, and the future of precision oncology.