Shawn R. Feaster
Papers
1
Total Citations
60
H-Index
1
About
Shawn R. Feaster is a distinguished researcher in chemical defense and neurotoxicology, best known for his work on countermeasures against organophosphate nerve agents. His most-cited study, "Oral administration of pyridostigmine bromide and huperzine A protects human whole blood cholinesterases from ex vivo exposure to soman" (2005, 60 citations), demonstrated a pioneering approach to pre-exposure prophylaxis. By combining pyridostigmine bromide with huperzine A, Feaster showed that oral administration could effectively shield human cholinesterase enzymes from the lethal effects of soman, a potent chemical warfare agent. This work has significant implications for military and civilian protection against chemical threats, offering a practical, non-invasive strategy for enhancing survivability. Feaster’s research bridges pharmacology and toxicology, providing a foundation for developing safer, more effective pretreatment regimens. His contributions have been instrumental in advancing our understanding of cholinesterase inhibition and reactivation, with his 2005 paper remaining a key reference in the field. Feaster’s work continues to inform ongoing efforts to mitigate the impact of nerve agent exposure, underscoring his role as a vital contributor to chemical defense science.
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Top Papers
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