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About

Shai Kaplan is a versatile researcher whose work spans systems biology, synthetic biology, and antimicrobial resistance surveillance. His most influential contributions emerge from the intersection of quantitative microbiology and high-throughput experimental platforms, leveraging robotic technologies to address fundamental and applied biological questions. Kaplan's landmark 2009 study on promoter activity distributions in *Escherichia coli*, now cited nearly 100 times, provided a comprehensive quantitative picture of how bacteria allocate their transcriptional resources across the genome — a foundational insight for understanding cellular economy. That same year, his work on the molecular implementation of logic programs (80 citations) demonstrated how biological circuits could be engineered to perform computational operations, contributing meaningfully to the emerging field of synthetic biology. More recently, Kaplan has turned his expertise in robotic assay design toward a pressing global health challenge: antimicrobial resistance. His development of the Robotic Antimicrobial Susceptibility Platform (RASP) offers a scalable, high-throughput solution for One Health surveillance of resistant pathogens, reflecting a commitment to translating laboratory innovation into real-world impact. Across his career, Kaplan exemplifies the power of combining automation, quantitative analysis, and biological insight to tackle diverse scientific challenges.