Sebastian Hans
Papers
6
Total Citations
131
H-Index
5
About
Sebastian Hans is a bioprocess engineering researcher whose work sits at the intersection of automation, microbial cultivation, and data-driven process development. His research focuses primarily on high-throughput mini-bioreactor platforms, robotic liquid handling, and multivariate analytics — tools that dramatically accelerate the development of microbial bioprocesses for industrial biotechnology applications. Hans's most significant contribution is the development and application of integrated robotic mini-bioreactor systems capable of running dozens of parallel cultivations simultaneously with automated online monitoring and process control. His 2019 paper on this platform has garnered 59 citations, reflecting its broad influence on how researchers approach early-stage bioprocess development. By combining sophisticated fed-batch and continuous cultivation strategies with multivariate prediction models, he has demonstrated how organisms such as *Saccharomyces cerevisiae* and *Escherichia coli* can be screened and optimized far more efficiently than through conventional methods. Beyond platform development, Hans has extended this automated framework to strain selection, knockout mutant screening, and enzyme characterization for nucleoside kinases relevant to cancer and antiviral drug development. With over 130 cumulative citations across his key publications, his work meaningfully advances the field's capacity to compress bioprocess development timelines while improving experimental rigor and reproducibility.
Research Focus
Key Achievements
Top Papers
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- 3Monitoring Parallel Robotic Cultivations with Online Multivariate Analysis18 citations · 2020
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