Sandra L. Grimm
Papers
2
Total Citations
67
H-Index
2
About
Sandra L. Grimm is a leading expert in high-throughput proteomics, with a primary focus on the development and application of reverse-phase protein array (RPPA) technology. Her major contributions center on advancing RPPA as a robust, antibody-based platform capable of quantifying hundreds of proteins across thousands of biological samples, including tissue lysates, serum, and plasma. Her seminal work, "Reverse-Phase Protein Array: Technology, Application, Data Processing, and Integration" (2021), has garnered over 67 citations, underscoring its significance as a comprehensive guide for researchers. This paper details the entire RPPA workflow—from robotic microspotting to data normalization and integration—enabling precise, high-throughput analysis of signaling pathways in diseases like cancer. Grimm’s efforts have been instrumental in standardizing RPPA protocols, making the technology more accessible for translational research. Her work is widely cited in studies exploring protein biomarkers and therapeutic targets, reflecting her impact on precision medicine. Through her innovations, Grimm has empowered researchers to bridge the gap between genomics and functional proteomics, solidifying her reputation as a key figure in the field.
Research Focus
Key Achievements
Top Papers
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