Ron Kerkhoven

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About

Ron Kerkhoven is a leading figure in functional genomics and microarray technology, whose work has significantly advanced the precision and scalability of nucleic acid printing. His key research areas encompass the development of novel surface chemistry and transfer methods for DNA and RNA microarrays, with a particular focus on enhancing the resolution and reproducibility of these critical tools. Kerkhoven’s most notable contribution is the pioneering "dendrimer-mediated transfer printing" technique, described in his highly cited 2007 paper (76 citations). This method revolutionized microarray fabrication by modifying PDMS stamps with dendrimers to create "dendri-stamps," enabling the transfer of DNA and RNA with submicron edge resolution. This innovation dramatically improved the accuracy and density of microarray features, facilitating more reliable high-throughput gene expression analysis. Beyond this landmark work, Kerkhoven has been instrumental in applying these technologies to large-scale genomic studies, and his contributions have been recognized through numerous collaborations in cancer genomics and molecular diagnostics. His work remains a cornerstone for researchers seeking to push the boundaries of microarray-based functional genomics.