Roman P Karas

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About

Roman P. Karas is a forensic chemist whose work has significantly advanced the detection and quantitation of cannabinoids in biological matrices. His primary research focuses on developing rapid, sensitive, and automated analytical methods for drugs of abuse, particularly tetrahydrocannabinol (THC) and its metabolites. Karas’s most cited work, a 2010 study on a fast method for screening and quantitation of THC and metabolites in urine using automated solid-phase extraction coupled with liquid chromatography-tandem mass spectrometry (SPE/LC/MS/MS), has garnered 20 citations. This contribution is notable for streamlining forensic toxicology workflows, reducing analysis time while maintaining high accuracy—a critical improvement for clinical and legal applications. By integrating automation, Karas’s method enhances reproducibility and throughput, addressing key challenges in drug testing laboratories. His work underscores the importance of efficient analytical techniques in forensic science, impacting both research and practical implementation in toxicology. Karas’s dedication to method optimization continues to support reliable drug monitoring, making his contributions valuable for students and professionals seeking to understand modern approaches to substance detection.