Papers
9
Total Citations
284
H-Index
8
About
Reto Crameri is a pioneering molecular allergologist whose career has been defined by his groundbreaking work in allergen discovery and characterization using phage display technology. Working primarily with complex allergenic systems—including molds, foods, mites, and the clinically significant fungus *Aspergillus fumigatus*—Crameri developed and refined high-throughput methodologies that transformed how researchers identify and clone allergen-encoding genes. His most influential contribution, detailed across several highly cited publications, was the innovative combination of phage surface-displayed cDNA libraries with high-density arrays and robotics-based screening. This powerful platform enabled the rapid, quantitative identification of IgE-binding molecules from complex biological sources—work that has accumulated over 260 citations across his key publications alone. His 2004 paper on cloning allergens via phage display (74 citations) and his 2003 high-throughput array methodology (57 citations) remain landmark references in the field. Crameri's long-term vision was to fully map the allergen repertoire of complex sources, ultimately enabling the reconstitution of complete allergenicity using standardized recombinant proteins—a goal with profound implications for allergy diagnostics and immunotherapy. His body of work represents a foundational bridge between molecular biology tools and clinical allergy research.
Research Focus
Key Achievements
Top Papers
- 1Cloning allergens via phage display74 citations · 2004
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- 3Tapping Allergen Repertoires by Advanced Cloning Technologies45 citations · 2001
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- 8Phage display as a tool for rapid cloning of allergenic proteins.8 citations · 2001
- 9Overview of Aspergillus Allergens3 citations · 2009