Andreas Limacher
Papers
1
Total Citations
13
H-Index
1
About
Andreas Limacher’s research bridges molecular immunology and fungal pathogenesis, with a particular focus on the structural biology of allergens from the opportunistic pathogen *Aspergillus fumigatus*. His most cited work, a 2006 study on the structural aspects and clinical relevance of *A. fumigatus* antigens and allergens, introduced a pioneering robotics-based high-throughput screening approach. By displaying cDNA libraries on phage surfaces, Limacher and his team identified at least 81 distinct structures capable of binding IgE from sensitized patients—a breakthrough that illuminated both species-specific and phylogenetically conserved allergenic determinants. This work has garnered 13 citations and remains a foundational reference for understanding fungal allergen diversity and its clinical implications in conditions like allergic bronchopulmonary aspergillosis. Limacher’s contributions have advanced the field by providing a systematic, structural framework for characterizing fungal immunogens, offering new avenues for diagnostic and therapeutic targeting. His research underscores the power of integrating automated screening with molecular biology to unravel complex host-pathogen interactions, making him a notable figure in allergology and fungal immunology.
Research Focus
Key Achievements
Top Papers
- 1