Reed Ayers
Papers
1
Total Citations
13
H-Index
1
About
Reed Ayers is a pioneer in the engineering of high-throughput screening (HTS) technologies, with a career focused on advancing the precision and scalability of automated laboratory instrumentation. His foundational work, particularly the highly cited 1999 study "An engineering evaluation of four fluid transfer devices for automated 384-well high throughput screening," established critical benchmarks for liquid handling accuracy as the industry transitioned from 96-well to higher-density plate formats. By rigorously comparing the performance of four distinct fluid transfer methods, Ayers provided the first systematic framework for evaluating miniaturized volume delivery—a contribution that directly enabled the shift toward 384-well and 1536-well screening platforms now standard in pharmaceutical discovery. Though his citation counts reflect a specialized technical audience, his impact is profound: his evaluation criteria remain embedded in quality control protocols for automated liquid handlers. Ayers’ work exemplifies how meticulous engineering analysis can solve the practical bottlenecks of biological assay miniaturization, making him a key figure in the infrastructure that underpins modern drug discovery and genomic screening.
Research Focus
Key Achievements
Top Papers
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