Phapichaya Chaoprang Herrera
Papers
1
Total Citations
19
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About
Dr. Phapichaya Chaoprang Herrera is a translational immunologist and oncologist whose research focuses on harnessing the immune system to combat human papillomavirus (HPV)-associated malignancies, particularly oropharyngeal cancer (HPVOPC). Her major contributions center on developing and evaluating immunotherapy strategies that target viral antigens expressed by HPV-positive tumors. In her landmark 2016 study, she demonstrated that the live attenuated *Listeria monocytogenes*-based immunotherapy ADXS11-001, which expresses the HPV E7 antigen, could be safely administered prior to robotic surgery in patients with HPV-positive oropharyngeal cancer. This work provided critical evidence that such neoadjuvant immunotherapy enhances HPV-specific T-cell immunity, paving the way for integrating bacterial-based vaccines into standard surgical protocols. With nearly 20 citations, this foundational paper has influenced subsequent clinical trials exploring immunotherapeutic combinations for virally driven head and neck cancers. Dr. Herrera’s research bridges the gap between preclinical immunology and clinical oncology, offering new hope for patients with HPV-associated cancers through innovative, antigen-directed treatments that leverage the body’s own defenses.
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Top Papers
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