Oliver Kepp

Université Paris-Sud, Inserm, Université Paris-Saclay

Papers

4

Total Citations

235

H-Index

3

About

Oliver Kepp is a leading researcher in cancer biology and immunology, with a primary focus on immunogenic cell death (ICD), autophagy modulation, and high-throughput screening technologies. His major contributions include demonstrating that the oncolytic peptide LTX-315 triggers ICD by selectively permeabilizing mitochondrial membranes, leading to caspase-independent necrosis and robust T cell-mediated antitumor immunity—a finding with 129 citations that has opened new avenues for cancer immunotherapy. Kepp also showed that IGF1 receptor inhibition amplifies the effects of cancer drugs through autophagy-dependent and immune mechanisms, a study with 77 citations that highlights his work on pharmacological autophagy enhancement for age-associated diseases. Additionally, he co-developed methods for quantifying cellular viability using automated microscopy and flow cytometry (26 citations), providing essential tools for preclinical research. His high-throughput screening approaches for autophagy (3 citations) further underscore his technical expertise. Kepp’s work bridges fundamental cell death mechanisms with translational applications, making him a key figure in the development of novel anticancer strategies.

Research Focus

Key Achievements

3
H-Index
4
Papers
235
Total Citations
59
Avg Citations/Paper
🏆 Most Cited Paper
The oncolytic peptide LTX-315 triggers immunogenic cell death
129 citations · 2016
📈 Most Prolific Year: 2021 (2 Papers)
🤝 Key Collaborators: 30
🏛 Institutions: Université Paris-Sud, Inserm, Université Paris-Saclay

Top Papers

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Key Collaborators

Contact & Links

Available for collaboration
Content generated · 13 days ago