Allan Sauvat
Papers
3
Total Citations
158
H-Index
3
About
Allan Sauvat is a prominent researcher in cell death and cancer immunology, best known for elucidating the mechanisms of immunogenic cell death (ICD). His seminal work on the oncolytic peptide LTX-315, published in 2016 and cited over 129 times, demonstrated that this agent triggers a unique form of necrosis by permeabilizing mitochondrial membranes, leading to a potent T lymphocyte-mediated anticancer immune response. This discovery has significant implications for developing novel cancer immunotherapies. Sauvat also made foundational contributions to methodology, co-authoring a widely used protocol for quantifying cellular viability via automated microscopy and flow cytometry (2015, 26 citations), which has become a standard technique in cell death research. Additionally, his work on high-throughput screening for autophagy (2021) showcases his expertise in advanced assay development. Through these achievements, Sauvat has advanced our understanding of how dying cells can activate the immune system, bridging cell biology and clinical oncology.
Research Focus
Key Achievements
Top Papers
- 1The oncolytic peptide LTX-315 triggers immunogenic cell death129 citations · 2016
- 2
- 3High throughput screening for autophagy3 citations · 2021