Nils Paust
Papers
4
Total Citations
41
H-Index
4
About
Nils Paust is a pioneering researcher in centrifugal microfluidics, dedicated to automating complex biomedical laboratory workflows that bridge cutting-edge diagnostics with practical clinical applications. His work centers on engineering "LabDisk" platforms that harness centrifugal forces to streamline labor-intensive sample preparation processes, dramatically reducing human error while improving reproducibility and sensitivity. Among his most significant contributions is the automation of tryptic digestion for proteomic mass spectrometry, enabling high-sensitivity protein identification and quantification in clinical settings — a breakthrough that has garnered 17 citations since its 2020 publication. He has also advanced whole genome sequencing workflows through automated library preparation, and developed innovative nanobead-based extraction techniques for cell-free circulating DNA, a critical emerging biomarker in cancer monitoring and infectious disease diagnostics. His MRD disk further exemplifies his translational vision, delivering multiplexed, highly sensitive qPCR for minimal residual disease tracking in cancer patients. With a cumulative citation record reflecting growing recognition across genomics, proteomics, and liquid biopsy research, Paust's work represents a compelling convergence of precision engineering and clinical need — offering researchers and clinicians alike powerful tools to accelerate diagnostics with greater accuracy and efficiency.
Research Focus
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Top Papers
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