Niklas Tenhaef
Papers
2
Total Citations
31
H-Index
2
About
Niklas Tenhaef is a leading figure in the automation of bioprocess development, whose work is fundamentally reshaping how microbial strains are engineered and optimized. His research centers on the robotic integration of laboratory-scale stirred tank bioreactors and the development of automated workflows for adaptive laboratory evolution (ALE). Tenhaef’s major contribution lies in demonstrating that classic, geometrically scalable stirred tank reactors can be operated autonomously, bridging the critical gap between high-throughput screening and industrial production. His 2021 paper on robotic integration, with 16 citations, established a model-driven framework for precise, unattended process control and monitoring, proving that lab-scale STRs can achieve the reliability of large-scale plants. Expanding on this foundation, his 2023 work on automated long-term ALE, garnering 15 citations, showcased a powerful, untargeted method for improving substrate utilization—specifically, ethanol consumption by *Corynebacterium glutamicum*. By combining robotics with evolutionary biology, Tenhaef has created a platform that accelerates strain development for sustainable biomanufacturing, making him a pivotal innovator in the field of synthetic biology and bioprocess engineering.
Research Focus
Key Achievements
Top Papers
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