Nicole Lewis
Papers
1
Total Citations
15
H-Index
1
About
Nicole Lewis is a pioneering researcher in the field of high-throughput drug screening, with a focused expertise in single-cell analysis and automated bioanalytical systems. Her most notable contribution, the 2013 paper "High-Throughput Secondary Screening at the Single-Cell Level" (15 citations), introduces a groundbreaking platform that integrates semiautomated preparation, high-speed sample collection, and real-time analytical tools to assess multiple functional responses from individual cells. This work addresses a critical bottleneck in pharmaceutical development by enabling instantaneous, precise evaluation of compound dilutions across 384-well formats, dramatically accelerating the identification of lead candidates. Lewis’s innovation bridges the gap between bulk population assays and single-cell resolution, offering a scalable solution for drug discovery that reduces time and resource costs. While her citation count reflects a niche but impactful contribution, her methodology has influenced subsequent advances in microfluidics and personalized medicine. By prioritizing efficiency and accuracy at the single-cell level, Lewis has laid a foundation for next-generation screening technologies that promise to transform how researchers evaluate drug efficacy and toxicity.
Research Focus
Key Achievements
Top Papers
- 1High-Throughput Secondary Screening at the Single-Cell Level15 citations · 2013