Muyang Ruan

Southern University of Science and Technology

Papers

Total Citations

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About

Muyang Ruan is pioneering the frontier of robotic intracellular surgery, with a focus on label-free, minimally invasive cellular manipulation. His most-cited work, "Label-free robotic mitochondrial biopsy" (2025, 5 citations), addresses a critical bottleneck in cellular probing: the reliance on fluorescent labeling, which can induce photodamage, cytotoxicity, and compromise downstream analyses. By developing a robotic micromanipulation system that operates without fluorescent markers, Ruan has opened new avenues for precise, high-fidelity extraction of subcellular components. This breakthrough not only enhances the accuracy of single-cell studies but also preserves the native state of biological samples, a key advantage for subsequent molecular and functional assays. Though early in its citation trajectory, this work signals a paradigm shift in how researchers approach intracellular operations, moving away from invasive optical techniques toward mechanical precision. Ruan’s contributions are particularly impactful for fields like mitochondrial biology, where clean, unperturbed samples are essential. His research stands at the intersection of robotics, nanotechnology, and cell biology, offering a powerful tool for probing the fundamental machinery of life with unprecedented subtlety.