Michelle Gentile

Papers

Total Citations

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About

Dr. Michelle Gentile is a head and neck surgical oncologist whose research focuses on the diagnosis and treatment of oropharyngeal carcinoma, particularly in cases of unknown primary origin. Her most notable work examines the long-term oncologic outcomes of patients with HPV-positive oropharyngeal carcinoma of unknown primary (CUP) following transoral robotic surgery (TORS). This study addresses a particularly challenging clinical scenario where the primary tumor site cannot be identified through conventional imaging or endoscopy. By demonstrating the efficacy of TORS as both a diagnostic and therapeutic tool, Dr. Gentile has contributed to evolving treatment algorithms that reduce the morbidity associated with traditional approaches like extensive radiation fields. Her research, which has garnered early citations, provides critical data on survival outcomes and quality of life for this rare patient population. Dr. Gentile’s work bridges the gap between minimally invasive surgical innovation and precision oncology, offering patients with HPV+ CUP a targeted, less toxic treatment pathway. Her contributions are shaping contemporary management strategies for head and neck cancers of unknown primary.