Michael R. DeFelippis
Papers
1
Total Citations
46
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1
About
Michael R. DeFelippis is a leading figure in biopharmaceutical characterization, with a primary research focus on the analytical development and structural analysis of therapeutic proteins, particularly monoclonal antibodies. His major contributions lie in advancing high-throughput, automated methodologies for the rapid profiling of critical quality attributes. Notably, he pioneered an automated robotic platform for the rapid oligosaccharide analysis of monoclonal antibodies directly from cell culture, a seminal 2013 work that has garnered 46 citations and revolutionized glycan screening efficiency in bioprocessing. This innovation enables real-time monitoring of product quality, significantly accelerating development timelines. DeFelippis’s work bridges the gap between complex analytical chemistry and practical biomanufacturing, impacting how the industry ensures consistency and safety of biologic drugs. His achievements underscore a career dedicated to integrating automation and analytical rigor, making him a key resource for students and researchers seeking to understand modern approaches to protein therapeutics analysis and quality control.
Research Focus
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Top Papers
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