Margaret Doherty
Papers
1
Total Citations
46
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1
About
Dr. Margaret Doherty is a leading figure in bioprocess engineering and analytical biotechnology, with a focused expertise in the characterization and quality control of therapeutic monoclonal antibodies. Her most impactful work centers on the development of high-throughput, automated platforms that bridge the gap between cell culture production and critical quality attribute analysis. Her landmark 2013 paper, "An automated robotic platform for rapid profiling oligosaccharide analysis of monoclonal antibodies directly from cell culture," which has garnered 46 citations, introduced a transformative method for directly analyzing glycosylation patterns—a key determinant of drug efficacy and safety—without the need for extensive sample purification. This innovation significantly accelerates process development and real-time monitoring in biomanufacturing. Dr. Doherty’s contributions are foundational for the industry’s push toward Process Analytical Technology (PAT) and Quality by Design (QbD), enabling faster, more reliable production of life-saving biologics. Her work continues to inspire researchers seeking to integrate automation and analytics for robust, scalable therapeutic manufacturing.
Research Focus
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Top Papers
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