Michael A. Baldwin
Papers
3
Total Citations
558
H-Index
3
About
Michael A. Baldwin is a prominent researcher in the field of proteomics and mass spectrometry, whose work has fundamentally advanced how scientists identify and analyze proteins from complex biological samples. His research centers on developing and refining mass spectrometric methodologies for protein identification, quantification, and the study of protein-protein interactions. Baldwin's most influential contributions include pioneering work on isotope-coded affinity tag (ICAT) technology, particularly the development of cleavable 13C-ICAT reagents combined with multidimensional chromatography, enabling differential protein profiling from extremely low-quantity, high-complexity samples — a landmark study that has garnered 295 citations. His widely cited review on protein identification by mass spectrometry (225 citations) stands as an authoritative resource documenting two decades of instrumental advances that made routine proteomic analysis possible. Additionally, his application of high-throughput MALDI-TOF tandem mass spectrometry to map protein-protein interactions within the nuclear pore complex of *Saccharomyces cerevisiae* demonstrates his breadth across structural and systems biology. Baldwin's cumulative impact reflects both technical innovation and accessibility — translating cutting-edge instrumentation into practical workflows that have empowered researchers worldwide to push the boundaries of proteomics research.
Research Focus
Key Achievements
Top Papers
- 1
- 2Protein Identification by Mass Spectrometry225 citations · 2003
- 3