Max H. Thayer
Papers
1
Total Citations
42
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1
About
Max H. Thayer is a leading figure in structural biology, with a primary focus on the optimization of macromolecular crystallization—a critical bottleneck in protein structure determination. His most influential work, "Efficient optimization of crystallization conditions by manipulation of drop volume ratio and temperature" (2007, 42 citations), introduced a powerful, high-throughput method that refines initial crystallization hits by systematically varying drop volume ratios and temperature. This approach dramatically reduces the time and material required to produce diffraction-quality crystals, enabling faster structural studies of complex biological molecules. Thayer’s contributions have been instrumental in streamlining the pipeline from gene to structure, directly impacting fields from drug design to enzymology. His work is widely recognized for its practical utility in both academic and industrial labs, and he continues to advance the automation and reproducibility of crystallization screens. With a career defined by methodical innovation, Thayer remains a key resource for researchers seeking efficient routes to high-resolution protein structures.
Research Focus
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Top Papers
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