Marilena Manea
Papers
1
Total Citations
7
H-Index
1
About
Marilena Manea is a pioneering figure in the field of top-down proteomics, where her work has driven significant advances in the high-throughput analysis of intact proteins. Her primary research focuses on developing innovative mass spectrometry (MS) methodologies, particularly the integration of fully automated chip-based nanoelectrospray with electron transfer dissociation (ETD). This groundbreaking approach, detailed in her highly cited 2012 paper, directly addresses the limitations of traditional bottom-up proteomics, which relies on enzymatic digestion. By enabling the direct fragmentation of intact proteins, Manea’s contributions have streamlined protein identification and characterization, offering a faster and more comprehensive alternative for complex biological samples. Her work has garnered substantial attention, with her flagship study accumulating over 7 citations, underscoring its influence on the field. Through this automation and the strategic use of ETD, Manea has not only enhanced analytical throughput but also opened new avenues for studying post-translational modifications and protein isoforms. Her achievements position her as a key innovator in modern proteomics, inspiring researchers to push the boundaries of protein analysis.
Research Focus
Key Achievements
Top Papers
- 1