Papers
10
Total Citations
249
H-Index
9
About
Maria Knikou is a leading neuroscientist whose research focuses on the neurorehabilitation of spinal cord injury (SCI), specifically the reorganization of spinal and corticospinal circuits to restore motor function. Her major contributions lie in understanding how the human spinal cord adapts to injury and how targeted interventions—such as robotic-assisted step training, transspinal stimulation, and paired brain-spinal cord stimulation—can induce neuroplasticity and improve walking. Her work has been highly influential, with her most-cited paper, "Functional reorganization of soleus H-reflex modulation during stepping after robotic-assisted step training in people with complete and incomplete spinal cord injury" (2013), garnering 50 citations. She has also published seminal studies on the modulation of spinal reflex circuits during stepping, including the phase-dependent preservation of the H-reflex in robotic exoskeletons and the effects of transspinal stimulation on inhibitory networks. Notably, her 2022 randomized clinical trial on combined brain and spinal cord paired stimulation demonstrated significant motor output facilitation, marking a key advance in neuromodulation for SCI. With over 200 total citations across her top papers, Knikou’s work bridges basic neurophysiology and clinical application, offering new hope for recovery in individuals with paralysis.
Research Focus
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