Margreet Bakker
Papers
1
Total Citations
25
H-Index
1
About
Margreet Bakker is a leading virologist whose work sits at the critical intersection of HIV evolution, epidemiology, and clinical pathogenesis. Her research is defined by a deep commitment to understanding how the genetic diversity of HIV-1 directly influences viral virulence and disease progression in human populations. A cornerstone of her contribution is her central role in the landmark BEEHIVE (Bridging the Evolution and Epidemiology of HIV in Europe) project, a massive collaborative effort to sequence and analyze nearly-complete viral genomes from over 3,000 HIV-1 infected individuals across Europe. Her highly cited 2016 paper on optimizing RNA extraction methods for high-throughput deep sequencing was instrumental in making this ambitious genomic surveillance possible, solving a fundamental technical bottleneck. This foundational work has enabled researchers to link specific viral genetic signatures to clinical outcomes, providing unprecedented insight into why HIV disease progresses at different rates in different people. With over 25 citations on this key methodological paper alone, Bakker’s expertise in viral genomics and molecular epidemiology continues to shape our understanding of HIV transmission, evolution, and the viral determinants of pathogenesis.
Research Focus
Key Achievements
Top Papers
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