Frank de Wolf
Papers
1
Total Citations
25
H-Index
1
About
Frank de Wolf is a leading epidemiologist and virologist whose research focuses on the evolutionary dynamics and clinical impact of HIV-1. He is best known for spearheading the BEEHIVE (Bridging the Evolution and Epidemiology of HIV in Europe) project, a landmark initiative that analyzes nearly-complete viral genomes from over 3,000 HIV-1 infected individuals across Europe. His major contributions include pioneering high-throughput deep sequencing methods to extract viral RNA from clinical samples, enabling unprecedented insights into how viral genetics drive virulence and transmission. His 2016 paper on comparing extraction methods for deep sequencing has garnered 25 citations, serving as a methodological cornerstone for the field. Through BEEHIVE, de Wolf has bridged molecular virology with population-level epidemiology, revealing how specific viral mutations correlate with disease progression. His work has profound implications for vaccine design and antiretroviral therapy, positioning him as a key figure in understanding HIV's genetic contribution to pathogenesis. By integrating large-scale genomic data with clinical outcomes, de Wolf continues to shape how researchers track and combat viral evolution in real time.
Research Focus
Key Achievements
Top Papers
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