Papers
27
Total Citations
1,241
H-Index
16
About
Dr. Marc C. Smaldone is a leading urologic oncologist whose research has fundamentally shaped the surgical management of kidney and prostate cancers. His most impactful work centers on the development and validation of the R.E.N.A.L. nephrometry score, a standardized system to objectively quantify renal tumor complexity. This innovation, detailed in his highly cited 2011 papers (277 and 163 citations), has revolutionized clinical decision-making, allowing surgeons to better predict complications and select the optimal approach—robotic, laparoscopic, or open—for partial nephrectomy. Dr. Smaldone has been a pivotal voice in the debate over surgical margins and resection techniques, leading a prospective multicenter study (93 citations) that clarified their impact on outcomes. His research extends to comparative effectiveness, demonstrating through large database analyses that robotic surgery, while increasing costs, offers comparable perioperative outcomes to open and pure laparoscopic approaches for complex renal lesions and radical prostatectomy. Notably, his early work also explored urinary biomarkers like nerve growth factor for interstitial cystitis. With over 900 citations across his top ten papers, Dr. Smaldone’s contributions provide the evidence base for modern, risk-stratified, and minimally invasive urologic oncology.
Research Focus
Key Achievements
Top Papers
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- 8Minimally Invasive Treatment of Vesicoureteral Reflux45 citations · 2008
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