Manlio Di Cristina

Papers

Total Citations

186

H-Index

About

Manlio Di Cristina is a leading researcher in infectious disease diagnostics, with a primary focus on developing high-throughput serological tools. His most influential work introduced antigen microarrays for the simultaneous detection of antibodies against multiple microbial pathogens, a breakthrough that transformed serodiagnosis by enabling rapid, multiplexed screening from a single serum sample. His landmark 2002 paper on antigen microarrays for serodiagnosis of infectious diseases has garnered 186 citations, underscoring its lasting impact on the field. By adapting robotic printing technology—originally developed for nucleic acid arrays—to protein-based platforms, Di Cristina demonstrated how to print microbial antigens in high-density formats, dramatically increasing assay throughput and specificity. This innovation has paved the way for more efficient surveillance of emerging infectious diseases and improved point-of-care diagnostics. His work remains foundational for researchers developing next-generation serological tests, and his contributions continue to influence the design of multiplex immunoassays used in both clinical and epidemiological settings.