Letizia Mezzasoma

Imperial College London, University of Perugia

Papers

Total Citations

256

H-Index

About

Letizia Mezzasoma is an Italian researcher whose work has made significant contributions to the field of infectious disease diagnostics, particularly through the innovative application of microarray technology. Her most influential research centers on the development of antigen microarrays for serodiagnosis, a groundbreaking approach that leverages robotic printing technology to simultaneously detect multiple antibodies in human sera. Her landmark 2002 paper, "Antigen Microarrays for Serodiagnosis of Infectious Diseases," has accumulated 186 citations and established a new paradigm for high-throughput serological testing. Building on this foundation, her 2003 follow-up study further refined the methodology, demonstrating its practical application for detecting antibodies against clinically significant pathogens including Toxoplasma gondii, rubella virus, cytomegalovirus, and herpes simplex virus types 1 and 2. By enabling the parallel interrogation of multiple infectious agents from a single serum sample, Mezzasoma's work dramatically improved diagnostic efficiency and accuracy. Her research has had a lasting impact on clinical microbiology and laboratory medicine, inspiring subsequent advances in multiplexed diagnostic platforms and contributing meaningfully to the broader field of protein microarray technology.