M.E. Rothenberg
Papers
1
Total Citations
22
H-Index
1
About
Dr. M.E. Rothenberg is a leading expert in the automation of cell-based assays for drug discovery, with a primary focus on advancing ADME/Tox (Absorption, Distribution, Metabolism, Excretion, and Toxicity) testing. Her seminal work, "Automation of Cell-Based Drug Absorption Assays in 96-Well Format Using Permeable Support Systems" (2012), revolutionized early-stage pharmaceutical screening by transitioning from traditional 24-well microplates to higher-throughput 96-well formats. This innovation dramatically increased the efficiency of permeability and transport studies using Caco-2 and MDCK-MDR1 cell lines, enabling faster identification of lead compounds with optimal drug-like properties. With 22 citations, this paper remains a cornerstone reference for researchers seeking to streamline preclinical workflows. Dr. Rothenberg’s contributions have directly accelerated the drug discovery pipeline by reducing manual labor and enhancing data reproducibility, making her a pivotal figure in the integration of automation and cell biology. Her work continues to inspire advancements in high-throughput screening, solidifying her reputation as a pioneer in pharmaceutical assay development.
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Top Papers
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