M. Yu. Donnikov
Papers
1
Total Citations
41
H-Index
1
About
M. Yu. Donnikov is a leading figure in the biophysics of DNA microarrays, whose work has fundamentally advanced our understanding of hybridization kinetics on solid supports. His research centers on the physical chemistry of nucleic acid interactions, particularly the transport and reaction dynamics that govern the performance of oligonucleotide microchips. Donnikov’s major contribution lies in elucidating how external mass transport of target DNA to immobilized probes, combined with the rates of duplex association and dissociation, determines the efficiency of single-nucleotide polymorphism discrimination. His highly cited 2006 paper (41 citations) provides a rigorous theoretical and experimental framework comparing hybridization on surface-based versus gel-based microchips, establishing design principles for optimal probe selection and mismatch detection. This work has had a lasting impact on the development of more accurate and sensitive diagnostic platforms, bridging the gap between fundamental biophysics and practical biochip engineering. Donnikov’s research continues to inform the design of next-generation microarray technologies, making him a key reference for students and researchers working in biosensor development, molecular diagnostics, and surface science.
Research Focus
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