M Matsuzaki

RIKEN Center for Brain Science, Tokyo University of Science

Papers

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About

M Matsuzaki is a pioneering neuroengineer whose work bridges robotics, neuroscience, and viral delivery technologies to unlock the secrets of motor control and cortical dynamics. Their key research areas include rodent motor learning, automated neural intervention, and primate neurotechnology. Matsuzaki’s major contributions are twofold: first, they developed a small-scale robotic manipulandum that enables precise study of motor learning in rodents, translating computational models from human research into animal models. This device, detailed in their 2021 paper (3 citations), allows researchers to apply force perturbations to rodent reach trajectories, opening new avenues for understanding neural plasticity. Second, Matsuzaki created ARViS, an automated injection robot for delivering virus to mouse and marmoset cerebral cortex (2024, 3 citations). This breakthrough enables accurate, fast, and dense delivery of genetically encoded fluorescent sensors across multiple cortical areas, facilitating the measurement of spatiotemporal dynamics in primate-specific brain activity. By overcoming the challenges of manual injections, ARViS promises to accelerate research into higher cognitive functions. Matsuzaki’s work is notable for its interdisciplinary impact, merging engineering precision with biological insight to advance our understanding of motor control and cortical computation.