Luis Schiappacasse

University of Lausanne, Hôpital Orthopédique de la Suisse Romande

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About

Luis Schiappacasse is a leading researcher in radiation oncology, with a focus on advancing stereotactic radiosurgery (SRS) and stereotactic body radiotherapy (SBRT) through algorithmic innovation. His most impactful contribution is the development and clinical validation of the VOLO™ inverse planning optimization algorithm for robotic radiosurgery, detailed in his highly cited 2019 paper (33 citations). This work demonstrated that VOLO™ significantly improves treatment planning efficiency and dosimetric quality for brain, spine, and prostate cases compared to the prior Sequential Optimization (SO) method, marking a major step forward in precision radiation delivery. Schiappacasse has also made notable contributions to neuro-oncology, particularly in understanding cystic vestibular schwannomas (VSs). His 2017 letter in *Neurosurgery* (5 citations) provided critical insight that cystic VSs respond best to radiosurgery, helping to refine treatment selection for this challenging tumor subtype. By bridging computational optimization with clinical application, Schiappacasse’s research directly enhances patient outcomes, making him a key figure in the evolution of modern, non-invasive cancer therapy.