Leticia Peris
Papers
1
Total Citations
33
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1
About
Leticia Peris is a leading cell biologist whose research focuses on the molecular mechanisms governing microtubule dynamics and neuronal function. Her major contributions center on the STOP (Stable Tubule Only Polypeptide) family of microtubule-associated proteins, which are critical for stabilizing neuronal microtubules and regulating synaptic plasticity. In her highly cited 2006 work (33 citations), Peris identified a novel member of this family—STOP-like Protein 21 (SL21)—revealing an unexpected Golgi localization for STOP proteins. This discovery fundamentally expanded the understanding of how microtubule stabilization is compartmentalized within neurons, linking cytoskeletal regulation to organelle positioning. Her work has profound implications for neurodevelopmental and psychiatric disorders, as STOP protein suppression in mice leads to severe synaptic and behavioral deficits. Peris’s research bridges basic cytoskeletal biology with neurological disease mechanisms, establishing her as a key figure in neuronal cell biology. Her findings continue to influence studies on microtubule-associated proteins, synaptic function, and the cellular basis of brain disorders, making her work essential reading for researchers in neuroscience and cell biology.
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