Papers
1
Total Citations
33
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1
About
Christophe Bosc is a cell biologist whose research focuses on the molecular architecture and dynamics of the cytoskeleton, with a particular emphasis on microtubule-associated proteins (MAPs). His major contributions center on the STOP (Stable Tubule Only Polypeptide) family of proteins, which are critical for stabilizing neuronal microtubules and regulating synaptic plasticity. In his most cited work, Bosc identified and characterized SL21 (STOP-like protein 21), a novel member of the STOP family, demonstrating for the first time that STOP proteins localize to the Golgi apparatus in addition to microtubules. This discovery expanded the understanding of how microtubule stabilization contributes to organelle positioning and neuronal function. With over 33 citations, this foundational study has influenced subsequent research on cytoskeletal regulation in both healthy neurons and neurodegenerative conditions. Bosc’s work bridges cell biology and neuroscience, providing key insights into how microtubule-associated proteins maintain neuronal structure and signaling. His findings continue to inform studies on synaptic deficits and behavioral abnormalities linked to microtubule instability.
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