Dominique Proietto
Commissariat à l'Énergie Atomique et aux Énergies Alternatives
Papers
1
Total Citations
33
H-Index
1
About
Dominique Proietto has made significant contributions to the understanding of neuronal microtubule dynamics, with a particular focus on the STOP (Stable Tubule Only Polypeptide) family of proteins. Her research centers on the molecular mechanisms underlying microtubule stabilization in neurons, a critical process for maintaining synaptic function and neural connectivity. In her most cited work, Proietto identified and characterized STOP-like Protein 21 (SL21) as a novel member of the STOP family, demonstrating its unexpected Golgi localization—a finding that expanded the known functional landscape of these proteins beyond their traditional roles in neuronal processes. This discovery, published in 2006 and garnering 33 citations, provided new insights into how microtubule-associated proteins may coordinate organelle positioning with cytoskeletal stability. By revealing that mature neurons express SL21 alongside the established E-STOP and N-STOP proteins, Proietto's work has helped illuminate the complexity of microtubule regulation in the brain. Her findings have implications for understanding synaptic plasticity and behavioral deficits observed when STOP proteins are suppressed, making her research foundational for those studying cytoskeletal contributions to neurological function.
Research Focus
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Top Papers
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