Papers
1
Total Citations
47
H-Index
1
About
Lei Xu is a leading figure in the development of microfluidic technologies for biomedical diagnostics, with a particular focus on digital nucleic acid amplification and point-of-care testing. His most impactful work centers on the innovative SlipChip platform, a microfluidic device that enables complex liquid handling without the need for pumps or valves. In his highly cited 2019 study, Xu introduced the Multistep SlipChip, a groundbreaking tool capable of generating serial dilution nanoliter arrays. This device automates the creation of concentration gradients directly on a chip, a fundamental process for biological assays. Demonstrating its clinical power, Xu applied the chip to quantify Hepatitis B viral load using digital loop-mediated isothermal amplification (LAMP), achieving precise, absolute quantification. This work, which has garnered 47 citations, showcases his ability to merge elegant engineering with pressing clinical needs, offering a low-cost, instrument-free solution for viral load monitoring in resource-limited settings.
Research Focus
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