Laure Fourel
Papers
1
Total Citations
128
H-Index
1
About
Laure Fourel’s research lies at the dynamic intersection of biophysics, cell biology, and biomaterials, where she investigates how mechanical and biochemical cues from the extracellular matrix govern cell behavior. Her most cited work, a 2011 study with 128 citations, reveals a pivotal insight: the mode of presentation of morphogenetic protein BMP-2 dictates its biological activity. By tethering BMP-2 to a soft biopolymeric film made of poly(lysine) and hyaluronan—rather than delivering it in solution—Fourel demonstrated a dramatic, matrix-bound effect on cell adhesion and migration. This finding challenges conventional soluble-factor paradigms and underscores the importance of microenvironmental context in morphogen signaling. Her contributions have advanced our understanding of how soft biomaterials can be engineered to direct cellular responses, with implications for tissue regeneration and wound healing. Fourel’s work bridges fundamental mechanobiology with translational biomaterial design, earning her recognition as a key figure in the study of cell–matrix interactions. Her research continues to inspire new strategies for presenting bioactive molecules in a physiologically relevant manner.
Research Focus
Key Achievements
Top Papers
- 1