Kenneth M. Bischoff
Agricultural Research Service, National Center for Agricultural Utilization Research
Papers
8
Total Citations
147
H-Index
7
About
Kenneth M. Bischoff is a microbiologist and bioengineering researcher whose work sits at the dynamic intersection of functional proteomics, laboratory automation, and bioenergy. Working primarily at the USDA Agricultural Research Service, Bischoff has made significant contributions to the development of automated robotic platforms for high-throughput screening and engineering of microbial systems, particularly yeasts, for cellulosic ethanol production. His most influential work (35 citations) introduced an automated plate assay system for screening cellulase mutants, establishing a foundational framework for plasmid-based functional proteomics at scale. Building on this, Bischoff engineered improved *Saccharomyces cerevisiae* strains capable of fermenting xylose — a critical pentose sugar in lignocellulosic biomass — using innovative multi-plasmid expression systems and automated yeast mating and transformation protocols. His research on *Kluyveromyces marxianus*, a thermotolerant yeast with broad substrate range, further expanded options for industrial bioethanol catalysts through automated UV-C mutagenesis approaches. Beyond ethanol, Bischoff extended his robotic workcell platform to biodiesel applications through lipase gene assembly and expression projects. Collectively, his body of work — accumulating over 140 citations — reflects a sustained commitment to accelerating biotechnology discovery through intelligent laboratory automation, with clear implications for renewable fuel commercialization.
Research Focus
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Top Papers
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