Kendall Carrasco
Papers
1
Total Citations
72
H-Index
1
About
Dr. Kendall Carrasco is a medicinal chemist whose work is reshaping the hit-to-lead optimization pipeline in drug discovery. Her primary research focuses on fragment-based drug design, synthetic methodology, and the automation of early-stage pharmaceutical development. Carrasco’s most influential contribution is the “Diversity-Oriented-Target-Focused-Synthesis” (DOTFS) approach, a groundbreaking integrated strategy that marries fragment growing with diversity-oriented synthesis. This methodology, detailed in her 2018 paper (72 citations), directly addresses a critical bottleneck: the slow, manual process of converting initial hits into viable lead compounds. By enabling a more time- and cost-efficient workflow, her work promises to accelerate the entire drug discovery timeline. Beyond this flagship publication, Carrasco’s research portfolio demonstrates a sustained commitment to bridging the gap between academic fragment screening and industrial-scale medicinal chemistry. Her innovative framework has been recognized as a significant step toward the long-sought goal of process automation in hit-to-lead optimization, marking her as a rising leader in the field of synthetic and medicinal chemistry.
Research Focus
Key Achievements
Top Papers
- 1