Karsten M. Poulsen

Duke University

Papers

3

Total Citations

44

H-Index

3

About

Karsten M. Poulsen is a leading researcher at the intersection of nanomedicine, bioanalytical chemistry, and automated high-throughput experimentation. His work focuses on the protein corona—the layer of biomolecules that forms around nanoparticles in biological fluids—and its critical role in determining nanoparticle behavior and safety. Poulsen’s major contributions include pioneering automated, low-cost proteomic workflows to systematically characterize the protein corona, enabling reproducible, large-scale studies. His 2022 paper on the concentration and composition of the protein corona as a function of incubation time and serum concentration (21 citations) introduced a fully automated approach, while his 2020 work on automation and low-cost proteomics (20 citations) established experimental methods for generating big data in this field. Most recently, his 2023 study combined lab automation with machine learning to predict nanoparticle-protein interactions (3 citations), opening new avenues for rational nanomaterial design. By merging robotics, proteomics, and computational modeling, Poulsen is transforming how researchers study nano-bio interfaces, making high-quality data accessible and accelerating the development of safer, more effective nanomedicines.

Research Focus

Key Achievements

3
H-Index
3
Papers
44
Total Citations
15
Avg Citations/Paper
🏆 Most Cited Paper
Concentration and composition of the protein corona as a function of incubation time and serum concentration: an automated approach to the protein corona
21 citations · 2022
📈 Most Prolific Year: 2022 (1 Papers)
🤝 Key Collaborators: 3
🏛 Institutions: Duke University

Top Papers

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Key Collaborators

Contact & Links

Available for collaboration
Content generated · 13 days ago