Jose Mi. Perdomo
Papers
1
Total Citations
98
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About
Jose Mi. Perdomo is a pioneer in automated immunocytochemistry, whose groundbreaking work transformed tissue staining from a labor-intensive manual process into a precise, high-throughput technique. His most influential contribution, the development of the first automated method for immunocytochemistry, is detailed in his highly cited 1988 paper (98 citations). Perdomo engineered the Code-On Immunology System, an IBM System II-driven triaxial robotic slide staining unit that leveraged a novel capillary action principle to apply, incubate, and sequentially remove reagents on planar glass slides. This innovation dramatically improved reproducibility and efficiency in diagnostic pathology and biomedical research, enabling consistent, high-quality staining for countless laboratories worldwide. By automating a previously tedious and error-prone procedure, Perdomo’s work laid the foundation for modern robotic immunohistochemistry platforms, accelerating cancer diagnosis and biomarker studies. His achievement remains a landmark in laboratory automation, demonstrating how engineering ingenuity can solve critical bottlenecks in biological science.
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