John M. Masterson

Cedars-Sinai Medical Center, Cornell University

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About

John M. Masterson is a pioneering urologic surgeon whose work centers on advancing minimally invasive surgical techniques for patients with autosomal dominant polycystic kidney disease (ADPKD). His major contributions lie in the development and refinement of robotic bilateral nephrectomy, offering a less invasive alternative to the traditional open approach for managing massively enlarged kidneys. Masterson’s research demonstrates the feasibility and safety of using both the da Vinci XI and the novel da Vinci Single Port platforms for this complex procedure, as detailed in his 2023 study (6 citations). He has further established the superiority of the robotic method by directly comparing surgical outcomes to open surgery in a 2025 study (1 citation), providing critical data that supports a paradigm shift in surgical management. By championing these innovative techniques, Masterson is significantly reducing patient morbidity and recovery times, making a profound impact on the quality of life for those with ADPKD. His work positions him as a leading voice in robotic urologic surgery and a key figure in shaping future standards of care for this challenging condition.