Jisen Tang
Papers
1
Total Citations
504
H-Index
1
About
Jisen Tang has made foundational contributions to the understanding of transient receptor potential (TRP) channels, particularly the thermosensitive TRPV subfamily. Their landmark 2004 study, “2-Aminoethoxydiphenyl Borate Is a Common Activator of TRPV1, TRPV2, and TRPV3,” with over 500 citations, revealed that 2-APB—previously known as a modulator of other ion channels—acts as a broad activator of heat-sensitive TRPV channels. This work provided a critical pharmacological tool for dissecting the molecular mechanisms of thermal sensation and nociception. By demonstrating that a single small molecule could activate multiple TRPV family members, Tang’s research advanced the understanding of how these channels integrate chemical and thermal stimuli. Their findings have had lasting impact on pain biology and drug discovery, offering a framework for targeting TRP channels in therapeutic contexts. Tang’s work remains a cornerstone for researchers exploring sensory transduction and ion channel pharmacology.
Research Focus
Key Achievements
Top Papers
- 12-Aminoethoxydiphenyl Borate Is a Common Activator of TRPV1, TRPV2, and TRPV3504 citations · 2004