Jason D. Salter
Papers
1
Total Citations
20
H-Index
1
About
Jason D. Salter is a virologist whose research focuses on the molecular interplay between host antiviral factors and HIV, particularly the APOBEC3 family of proteins. His most notable contribution is the discovery of a novel class of antiretroviral compounds that protect APOBEC3 from HIV’s Vif protein, thereby restoring innate immunity against the virus. This work, published in 2018 and garnering 20 citations, represents a paradigm shift in HIV therapy by targeting host defenses rather than viral enzymes. Salter’s research has illuminated how APOBEC3 proteins are degraded by HIV Vif, and his identification of small-molecule inhibitors that block this degradation opens new avenues for drug development. His findings have been recognized for their potential to overcome drug resistance and enhance natural immune responses. Through his innovative approach, Salter has positioned himself at the forefront of host-directed antiviral strategies, offering hope for more durable and less toxic treatments for HIV infection.
Research Focus
Key Achievements
Top Papers
- 1