Jacob J. Schmidt
California NanoSystems Institute, University of California, Los Angeles
Papers
2
Total Citations
93
H-Index
2
About
Jacob J. Schmidt is a leading figure in bioengineering and biophysics, best known for pioneering high-throughput platforms for studying ion channels and membrane proteins. His major contributions center on the development of automated, scalable methods for forming artificial lipid bilayers—a critical technology for drug screening, toxin detection, and fundamental channel research. His seminal 2008 paper, “Ion channel and toxin measurement using a high throughput lipid membrane platform,” has garnered 64 citations, establishing a foundation for rapid, parallelized membrane assays. Building on this, his 2010 work on “Automatable lipid bilayer formation and ion channel measurement using sessile droplets” (29 citations) introduced a droplet-based approach that dramatically simplified and accelerated membrane formation, replacing slow, labor-intensive techniques with a robust, automatable process. These innovations have enabled broader access to ion channel electrophysiology, impacting both academic labs and biotech applications. Schmidt’s work bridges engineering and biology, making him a key contributor to the miniaturization and automation of membrane-based sensors and diagnostic tools.
Research Focus
Key Achievements
Top Papers
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