J. Andrew Duty
Papers
1
Total Citations
27
H-Index
1
About
Dr. J. Andrew Duty is a leading virologist whose research focuses on human cytomegalovirus (CMV) biology and the development of novel antiviral strategies. His most impactful work centers on identifying and characterizing neutralizing epitopes on essential CMV envelope proteins, with the goal of advancing immunotherapies and vaccines. In his highly cited 2016 study, Duty conducted a functional screen for anti-CMV biologics, discovering a broadly neutralizing epitope on the gH/gL/gO trimer—a glycoprotein complex critical for viral entry into all cell types. This work provided key insights into the structural vulnerabilities of CMV and demonstrated a pathway for targeting essential envelope components to achieve broad neutralization. With 27 citations, this study has influenced subsequent efforts in antibody engineering and vaccine design against this pervasive pathogen. Duty’s contributions are particularly significant given CMV’s role as a leading cause of congenital infection and a major complication in immunocompromised patients. His research continues to bridge fundamental virology and translational medicine, offering promising avenues for therapeutic intervention.
Research Focus
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Top Papers
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