I. K. Mosevich
Papers
2
Total Citations
8
H-Index
2
About
I. K. Mosevich is a pioneering radiochemist whose work lies at the intersection of asymmetric synthesis and molecular imaging. Her research focuses on developing novel, high-specific-activity radiotracers for Positron Emission Tomography (PET), a critical tool for studying neurological disorders and cancer in vivo. Mosevich's major contributions include the asymmetric synthesis of L-[β-11C]-3,4-Dihydroxyphenylalanine (L-[β-11C]DOPA), a key radiotracer for imaging dopaminergic function. This work, published in 2002, achieved 5 citations and demonstrated the use of a chiral Ni(II) complex (Ni-BPB-Gly) to produce enantiomerically pure amino acids—a significant advance in radiochemistry. She also developed methods for preparing [18F]fluorobenzyl bromides, enabling the asymmetric synthesis of fluorinated α-amino acids (3 citations). These contributions are notable for their impact on the design of radiotracers with precise stereochemistry, enhancing PET imaging accuracy. Mosevich's achievements underscore her role in bridging organic synthesis and nuclear medicine, providing foundational tools for non-invasive brain imaging and cancer diagnostics. Her work remains a reference for researchers seeking to optimize radiotracer production for clinical and preclinical applications.
Research Focus
Key Achievements
Top Papers
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